(KO Validated) CCND3 Polyclonal Antibody
Product Sizes
(KO Validated) CCND3 Polyclonal Antibody
£588.00
RD80131A-120UL
About this Product
- SKU:
- RD80131A-120UL
- Additional Names:
- CCND3,cyclin D3,Cyclin D3
- Application:
- Western Blot
- Buffer:
- PBS with 0.02% sodium azide, 50% glycerol, pH7.3
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activtiy is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. The CDK4 activity associated with this cyclin was reported to be necessary for cell cycle progression through G2 phase into mitosis after UV radiation. Several transcript variants encoding different isoforms have been found for this gene.
- Gene Details:
- CCND3
- Host:
- Rabbit
- Immunogen:
- Recombinant fusion protein of human CCND3 (NP_001751.1).
- Isotype:
- IgG
- Protein Details:
- P30281
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Size:
- 120 ul
- Supplier:
- Reddot
- Type:
- Antibody: Polyclonal Antibody
- Synonyms:
- D3-type cyclin;G1/S-specific cyclin-D3
- Manufacturer's Data Sheet:https://www.reddotbiotech.ca/antibodies/product/20941/KO_Validated_CCND3_Polyclonal_Antibody/