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Antibodies

Cleaved-CASP3 p17 (D175) Polyclonal Antibody

Product Sizes
Cleaved-CASP3 p17 (D175) Polyclonal Antibody
RD70663A-200UL
Academic Pricing
Please contact us for academic pricing.
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About this Product
SKU:
RD70663A-200UL
Additional Names:
A830040C14Rik,Apopain,CASP-3,CASP3,CASP3,Casp3a,Caspase 3,Caspase 3,apoptosis-related cysteine peptidase,Caspase 3,apoptosis-related cysteine protease,Caspase 3,apoptosis-related cysteine protease a,Caspase-3 subunit p12,CC3,CPP-32,CPP32,CPP32B,Cysteine protease CPP32,EC 3.4.22.56,LICE,mldy,OTTHUMP00000165052,OTTHUMP00000165053,OTTHUMP00000165054,PARP cleavage protease,Procaspase3,Protein Yama,SCA 1,SCA-1,SREBP cleavage activity 1,Yama
Application:
ELISA, IHC-Paraffin, Immunofluorescence, Immunohistochemistry, Western Blot
Buffer:
PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin.
Gene Details:
CASP3
Host:
Rabbit
Immunogen:
Synthesized peptide derived from the Internal region of human Caspase-3 p17
Isotype:
IgG
Protein Details:
P42574
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Size:
200 ul
Supplier:
Reddot
Type:
Antibody: Polyclonal Antibody
Synonyms:
apopain;CASP-3;caspase 3, apoptosis-related cysteine peptidase;caspase 3, apoptosis-related cysteine protease;caspase-3;CPP32;CPP-32;CPP32B;cysteine protease CPP32;PARP cleavage protease;procaspase3;protein Yama;SCA-1;SREBP cleavage activity 1