ROCK1 Polyclonal Antibody
Product Sizes
ROCK1 Polyclonal Antibody
£829.00
RD70331A-200UL
About this Product
- SKU:
- RD70331A-200UL
- Additional Names:
- coiled-coil-containing protein kinase 1,coiled-coil-containing protein kinase I,MGC131603,MGC43611,p160 Rhoassociated coiled coil-forming protein kinase,p160 ROCK-1,p160 ROCK1,p160ROCK,PRO0435,Renal carcinoma antigen NY REN 35,Renal carcinoma antigen NY-REN-35,Rho associated coiled coil containing protein kinase 1,Rho associated protein kinase 1,Rho kinase,Rho-alpha kinase,Rho-associated,Rho-associated protein kinase 1,ROCK I,ROCK-I,ROCK1,ROCK1,Rok,rokalpha
- Application:
- Immunohistochemistry
- Buffer:
- PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4
- Clonality:
- Polyclonal
- Concentration:
- 300 ug/ml
- Extra Details:
- This gene encodes a protein serine/threonine kinase that is activated when bound to the GTP-bound form of Rho. The small GTPase Rho regulates formation of focal adhesions and stress fibers of fibroblasts, as well as adhesion and aggregation of platelets and lymphocytes by shuttling between the inactive GDP-bound form and the active GTP-bound form. Rho is also essential in cytokinesis and plays a role in transcriptional activation by serum response factor. This protein, a downstream effector of Rho, phosphorylates and activates LIM kinase, which in turn, phosphorylates cofilin, inhibiting its actin-depolymerizing activity.
- Host:
- Rabbit
- Immunogen:
- KLH conjugated Synthetic peptide corresponding to Mouse Rock1
- Isotype:
- IgG
- Protein Details:
- P70335, Q63644
- Purification:
- Affinity Purified
- Reactivities:
- Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Size:
- 200 ul
- Supplier:
- Reddot
- Type:
- Antibody: Polyclonal Antibody
- Synonyms:
- Liver regeneration-related protein LRRG199;p150 RhoA-binding kinase ROK beta;p160 ROCK-1;Rho-associated, coiled-coil-containing protein kinase 1;Rho-associated, coiled-coil-containing protein kinase I
- Manufacturer's Data Sheet:https://www.reddotbiotech.ca/antibodies/product/20500/ROCK1_Polyclonal_Antibody/