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Antibodies

INS Polyclonal Antibody

Product Sizes
INS Polyclonal Antibody
£829.00
RD267409A-200UL
Academic Pricing
Please contact us for academic pricing.
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About this Product
SKU:
RD267409A-200UL
Additional Names:
IDDM,IDDM1,IDDM2,ILPR,IRDN,MODY10,INS,Insulin,insulin
Application:
Immunofluorescence, Immunohistochemistry
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Concentration:
1 mg/ml
Extra Details:
After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants.
Host:
Rabbit
Immunogen:
Recombinant fusion protein of human INS (NP_000198.1).
Isotype:
IgG
Protein Details:
P01308
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Size:
200 ul
Supplier:
Reddot
Type:
Antibody