(KO Validated) CTCF Polyclonal Antibody
Product Sizes
(KO Validated) CTCF Polyclonal Antibody
£874.00
RD267371A-200UL
About this Product
- SKU:
- RD267371A-200UL
- Additional Names:
- Transcriptional repressor CTCFL,Brother of the regulator of imprinted sites,CCCTC-binding factor,CTCF paralog,CTCF-like protein,Cancer/testis antigen 27,CT27,Zinc finger protein CTCF-T,CTCFL,BORIS
- Application:
- Western Blot
- Buffer:
- PBS with 0.02% sodium azide, 50% glycerol, pH7.3
- Concentration:
- 1 mg/ml
- Extra Details:
- This gene is a member of the BORIS + CTCF gene family and encodes a transcriptional regulator protein with 11 highly conserved zinc finger (ZF) domains. This nuclear protein is able to use different combinations of the ZF domains to bind different DNA target sequences and proteins. Depending upon the context of the site, the protein can bind a histone acetyltransferase (HAT)-containing complex and function as a transcriptional activator or bind a histone deacetylase (HDAC)-containing complex and function as a transcriptional repressor. If the protein is bound to a transcriptional insulator element, it can block communication between enhancers and upstream promoters, thereby regulating imprinted expression. Mutations in this gene have been associated with invasive breast cancers, prostate cancers, and Wilms' tumors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- Host:
- Rabbit
- Immunogen:
- Recombinant protein of human CTCF.
- Isotype:
- IgG
- Protein Details:
- P49711
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Size:
- 200 ul
- Supplier:
- Reddot
- Type:
- Antibody
- Synonyms:
- 11-zinc finger protein;CCCTC-binding factor;CTCFL paralog
- Manufacturer's Data Sheet:https://www.reddotbiotech.ca/antibodies/product/33497/KO_Validated_CTCF_Polyclonal_Antibody/