A2M Polyclonal Antibody
Product Sizes
A2M Polyclonal Antibody
£512.00
RD266765A-120UL
About this Product
- SKU:
- RD266765A-120UL
- Additional Names:
- A2M,A2MD,CPAMD5,FWP007,S863-7
- Application:
- Immunohistochemistry
- Buffer:
- PBS with 0.02% sodium azide, 50% glycerol, pH7.3
- Concentration:
- 1 mg/ml
- Extra Details:
- The protein encoded by this gene is a protease inhibitor and cytokine transporter. It uses a bait-and-trap mechanism to inhibit a broad spectrum of proteases, including trypsin, thrombin and collagenase. It can also inhibit inflammatory cytokines, and it thus disrupts inflammatory cascades. Mutations in this gene are a cause of alpha-2-macroglobulin deficiency. This gene is implicated in Alzheimer's disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. A related pseudogene, which is also located on the p arm of chromosome 12, has been identified.
- Host:
- Rabbit
- Immunogen:
- Recombinant fusion protein of human A2M (NP_000005.2).
- Isotype:
- IgG
- Protein Details:
- P01023
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Size:
- 120 ul
- Supplier:
- Reddot
- Type:
- Antibody
- Synonyms:
- C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5
- Manufacturer's Data Sheet:https://www.reddotbiotech.ca/antibodies/product/33160/A2M_Polyclonal_Antibody/