ABL1 Polyclonal Antibody
Product Sizes
ABL1 Polyclonal Antibody
£203.00
RD240438A-20UL
About this Product
- SKU:
- RD240438A-20UL
- Additional Names:
- Abelson murine leukemia viral oncogene homolog 1, Abelson tyrosine protein kinase 1, Abl 1, ABL, bcr/abl, c ABL, c abl oncogene 1 receptor tyrosine kinase, JTK7, p150, Proto-oncogene c-Abl, Tyrosine-protein kinase ABL1, v abl
- Application:
- Immunohistochemistry
- Buffer:
- PBS with 0.05% Proclin300, 50% glycerol, pH7.3
- Concentration:
- 0.24 mg/ml
- Extra Details:
- The ABL1 protooncogene encodes a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress response. Activity of c-Abl protein is negatively regulated by its SH3 domain, and deletion of the SH3 domain turns ABL1 into an oncogene. The t(9;22) translocation results in the head-to-tail fusion of the BCR (MIM:151410) and ABL1 genes present in many cases of chronic myelogeneous leukemia. The DNA-binding activity of the ubiquitously expressed ABL1 tyrosine kinase is regulated by CDC2-mediated phosphorylation, suggesting a cell cycle function for ABL1.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Tyrosine-protein kinase ABL1 protein
- Isotype:
- IgG
- Protein Details:
- P00519
- Purification:
- Affinity Purified
- Reactivities:
- Human, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Size:
- 20 ul
- Supplier:
- Reddot
- Type:
- Antibody
- Synonyms:
- Abelson murine leukemia viral oncogene homolog 1;Abelson tyrosine-protein kinase 1;p150;Proto-oncogene c-Abl
- Manufacturer's Data Sheet:https://www.reddotbiotech.ca/antibodies/product/29396/ABL1_Polyclonal_Antibody/