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Antibodies

AB42 Polyclonal Antibody

Product Sizes
AB42 Polyclonal Antibody
£759.00
RD240074A-200UL
Academic Pricing
Please contact us for academic pricing.
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About this Product
SKU:
RD240074A-200UL
Additional Names:
A4 amyloid protein,A4,AAA,ABETA,ABPP,AD1,AICD-50,AICD-57,AICD-59,AID(50),AID(57),AID(59),Alzheimer disease amyloid protein,Amyloid beta (A4) precursor protein,Amyloid beta A4 protein,Amyloid beta protein,Amyloid intracellular domain 50,Amyloid intracellular domain 57,Amyloid intracellular domain 59,Amyloid precursor protein,APP,APPI,Beta amyloid peptide,Beta-amyloid precursor protein,Beta-APP40,Beta-APP42,C31,Cerebral vascular amyloid peptide,CTFgamma,CVAP,Gamma-CTF(50),Gamma-CTF(57),Gamma-CTF(59),peptidase nexin II,PN 2,PN II,PN-II,PN2,PreA4,Protease nexin II,Protease nexin-II,S-APP-alpha,S-APP-beta
Application:
Immunohistochemistry
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Concentration:
2 mg/ml
Extra Details:
AB Beta derives from APP via proteolytic cleavage by proteases called A Alpha-, B Beta- and G Gamma-secretase. The A Alpha-secretase cleavage precludes the formation of AB Beta, while the B Beta- and G Gamma-cleavages generate APP components with amyloidogenic features. Amyloid beta A4 precursor protein(APP), encoded by APP gene which locate on human chromosome 21q, is a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. APP expressed in all fetal tissues and is pronounced in brain, kidney, heart and spleen, but weak in liver. Defects in APP are the cause of Alzheimer disease type 1 (AD1). This antibody can recogniaze the N-terminus of human APP: Soluble APP-alpha and Soluble APP-beta.
Host:
Rabbit
Immunogen:
Recombinant Mouse Beta-amyloid protein 42 protein
Isotype:
IgG
Protein Details:
P05067
Purification:
Affinity Purified
Reactivities:
Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Size:
200 ul
Supplier:
Reddot
Type:
Antibody
Synonyms:
ABPP;Alzheimer disease amyloid protein;Amyloid precursor protein;Amyloid-beta precursor protein;APPI;Cerebral vascular amyloid peptide;PreA4;Protease nexin-II