CASP1 Polyclonal Antibody
Product Sizes
CASP1 Polyclonal Antibody
£217.00
RD218207A-20UL
About this Product
- SKU:
- RD218207A-20UL
- Additional Names:
- CASP-1,CASP1,CASP1,Caspase 1,Caspase-1 subunit p10,ICE,IL-1 beta-converting enzyme,IL-1BC,IL1 beta converting enzyme,IL1B convertase,Interleukin 1 beta convertase,Interleukin 1B converting enzyme,Interleukin-1 beta convertase,Interleukin-1 beta-converting enzyme,p45
- Application:
- ELISA, Immunohistochemistry, Western Blot
- Buffer:
- PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
- Clonality:
- Polyclonal
- Concentration:
- 0.4 mg/ml
- Extra Details:
- This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This gene was identified by its ability to proteolytically cleave and activate the inactive precursor of interleukin-1, a cytokine involved in the processes such as inflammation, septic shock, and wound healing. This gene has been shown to induce cell apoptosis and may function in various developmental stages. Studies of a similar gene in mouse suggest a role in the pathogenesis of Huntington disease. Alternative splicing results in transcript variants encoding distinct isoforms.
- Host:
- Rabbit
- Immunogen:
- Fusion protein of human CASP1
- Isotype:
- IgG
- Protein Details:
- P29466
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Size:
- 20 ul
- Supplier:
- Reddot
- Type:
- Antibody: Polyclonal Antibody
- Synonyms:
- Interleukin-1 beta convertase;Interleukin-1 beta-converting enzyme;p45
- Manufacturer's Data Sheet:https://www.reddotbiotech.ca/antibodies/product/30926/CASP1_Polyclonal_Antibody/