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Antibodies

APC Polyclonal Antibody

Product Sizes
APC Polyclonal Antibody
£217.00
RD217831A-20UL
Academic Pricing
Please contact us for academic pricing.
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About this Product
SKU:
RD217831A-20UL
Additional Names:
Adenomatous Polyposis Coli,Adenomatous polyposis coli protein,Apc,APC,CC1,Deleted in polyposis 2.5,DP2,DP2.5,DP3,FAP,FPC,GS,Protein APC
Application:
ELISA, Immunohistochemistry
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Clonality:
Polyclonal
Concentration:
1.1 mg/ml
Extra Details:
This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product.
Host:
Rabbit
Immunogen:
Synthetic peptide of human APC
Isotype:
IgG
Protein Details:
P25054
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Size:
20 ul
Supplier:
Reddot
Type:
Antibody: Polyclonal Antibody
Synonyms:
Deleted in polyposis 2.5