Anti-Human CD274/PD-L1 Monoclonal Antibody(PE Conjugated)
Product Sizes
Anti-Human CD274/PD-L1 Monoclonal Antibody(PE Conjugated)
£476.00
RD21667F-200TESTS
About this Product
- SKU:
- RD21667F-200TESTS
- Additional Names:
- B7-H1, PD-L1,Programmed cell death ligand 1,B7 homolog 1,B7-H, B7H1, PDL1, PDCD1L1, PDCD1LG1
- Application:
- Flow Cytometry
- Buffer:
- PBS with 0.05% Proclin300, 1% BSA
- Clone:
- 29E.2A3
- Clonality:
- Monoclonal
- Conjugate:
- R-PE
- Extra Details:
- CD274, also known as PD-L1 and B7-H1, is type I transmembrane glycoprotein that serves as a ligand for CD279 (PD-1). This interaction is believed to regulate the balance between the stimulatory and inhibitory signals needed for responses to microbes and maintenance of self-tolerance. CD274 is involved in the costimulation of T cell proliferation and IL-10 and IFN-G Gamma production in an IL-2-dependent and CD279-independent manner. Conflicting data has shown that CD274 can inhibit T cell proliferation and cytokine production, and alternatively, enhance T cell activation. Other studies suggest that CD274 may signal bidirectionally, raising interesting implications for its expression in a wide variety of cell types, including T and B cells, antigen-presenting cells, and nonhematopoietic cells.
- Gene Details:
- CD274
- Host:
- Mouse
- Isotype:
- IgG2b, kappa
- Protein Details:
- Q9NZQ7
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8[o]C Do not freeze. Protect from light.
- Size:
- 200 tests
- Supplier:
- Reddot
- Type:
- Antibody: Monoclonal Antibody
- Synonyms:
- B7 homolog 1;B7-H;B7H1;CD274 antigen;hPD-L1;PDCD1 ligand 1;PDCD1L1;PDCD1LG1;PDL1;PD-L1;programmed cell death 1 ligand 1