Anti-Mouse CD274/PD-L1 Monoclonal Antibody(PE Conjugated)
Product Sizes
Anti-Mouse CD274/PD-L1 Monoclonal Antibody(PE Conjugated)
£221.00
RD21657F-100TESTS
About this Product
- SKU:
- RD21657F-100TESTS
- Additional Names:
- B7-H1, PD-L1,Programmed cell death ligand 1,B7 homolog 1,B7-H, B7H1, PDL1, PDCD1L1, PDCD1LG1
- Application:
- Flow Cytometry
- Buffer:
- PBS with 0.05% Proclin300, 1% BSA
- Clone:
- 10F.9G2
- Clonality:
- Monoclonal
- Conjugate:
- R-PE
- Extra Details:
- CD274, also known as B7-H1 or programmed death ligand 1 (PD-L1), is a 40 kD type I transmembrane protein and a member of the B7 family within the immunoglobulin receptor superfamily. It is expressed on T cells, B cells, NK cells, dendritic cells, IFN-G Gamma activated endothelial cells, and monocytes. B7-H1 is one of the ligands of PD-1. The interaction of B7-H1 with PD-1 plays an important role in the inhibition of T cell responses. Other studies have shown that B7-H1 is able to costimulate T cell growth and cytokine production. CD274 is involved in costimulation essential for T cell proliferation and production of IL-10 and IFN-G Gamma, in an IL-2-dependent and a PD-1-independent manner. Its interaction with PD-1 inhibits T cell proliferation and cytokine production.
- Gene Details:
- Cd274
- Host:
- Rat
- Isotype:
- IgG2b, kappa
- Protein Details:
- Q9EP73
- Reactivities:
- Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8[o]C Do not freeze. Protect from light.
- Size:
- 100 tests
- Supplier:
- Reddot
- Type:
- Antibody: Monoclonal Antibody
- Synonyms:
- A530045L16Rik;B7 homolog 1;B7h1;PD-;PDCD1 ligand 1;Pdcd1l;Pdcd1l1;Pdcd1lg1;Pdl1;programmed cell death 1 ligand 1