Anti-Human CD40 Monoclonal Antibody(AF488 Conjugated)
Product Sizes
Anti-Human CD40 Monoclonal Antibody(AF488 Conjugated)
£671.00
RD20566F-200TESTS
About this Product
- SKU:
- RD20566F-200TESTS
- Additional Names:
- Tumor necrosis factor receptor superfamily member 5,Cd40,B-cell surface antigen CD40,Bp50,CD40L receptor,CD40,Tnfrsf5
- Application:
- Flow Cytometry
- Buffer:
- PBS with 0.05% Proclin300, 1% BSA
- Clone:
- 3A8
- Clonality:
- Monoclonal
- Conjugate:
- Alexa Fluor® 488
- Extra Details:
- CD40 is a 48 kD type I glycoprotein also known as BP50. It is a member of the TNFR superfamily primarily expressed on B cells, macrophages, follicular dendritic cells, endothelial cells, fibroblasts, and at low levels on plasma cells. CD40 has been reported to be involved in B cell differentiation, costimulation, isotype class-switching, and protection of B cells from apoptosis. Additionally, CD40 is important for T cell-B cell interactions. The ligand of CD40 is CD154 (CD40 ligand). The 5C3 antibody has been reported to promote B cell proliferation in the presence of anti-IgM, IL-4 or PMA, partially blocking CD40 binding to CD40L, and B cells rescue from apoptosis.
- Gene Details:
- CD40
- Host:
- Mouse
- Isotype:
- IgG2a, kappa
- Protein Details:
- P25942
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8[o]C Do not freeze. Protect from light.
- Size:
- 200 tests
- Supplier:
- Reddot
- Type:
- Antibody: Monoclonal Antibody
- Synonyms:
- B cell surface antigen CD40;B cell-associated molecule;B-cell surface antigen CD40;Bp50;CD40 molecule, TNF receptor superfamily member 5;CD40L receptor;CDW40;p50;TNFRSF5;tumor necrosis factor receptor superfamily member 5