AF/LE Purified Anti-Mouse CD45R/B220 Antibody[RA3.3A 1/6.1]
Product Sizes
50 ug
£220.00
E-AB-F11120-50UG
500 ug
£541.00
E-AB-F11120-500UG
1 mg
£755.00
E-AB-F11120-1MG
About this Product
- SKU:
- E-AB-F11120
- Additional Names:
- B220
- Application:
- Cell-based/Functional Assay, Depletion, Flow Cytometry
- Buffer:
- 0.2 uM PBS
- Clone:
- RA3.3A 1/6.1
- Clonality:
- Monoclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- CD45R, also known as B220, is an isoform of CD45. It is a member of the protein tyrosine phosphatase (PTP) family with a molecular weight of approximately 180-240 kD. CD45R is expressed on B cells (at all developmental stages from pro-B cells through mature B cells), activated B cells, and subsets of T and NK cells. CD45R (B220) is also expressed on a subset of abnormal T cells involved in the pathogenesis of systemic autoimmunity in MRL-Faslpr and MRL-Fasgld mice. It plays a critical role in TCR and BCR signaling. The primary ligands for CD45 are galectin-1, CD2, CD3, and CD4. CD45R is commonly used as a pan-B cell marker; however, CD19 may be more appropriate for B cell specificity.
- Host:
- Rat
- Reactivities:
- Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8[o]C Do not freeze.
- Supplier:
- Elabscience
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:p-af_le_purified_anti_mouse_cd45r_b220_antibody_ra3.3a_1_6.1_e_ab_f11120-176597.html