AF/LE Purified Anti-Human CD8a Antibody[OKT-8]
Product Sizes
50 ug
£198.00
E-AB-F11100-50UG
500 ug
£380.00
E-AB-F11100-500UG
1 mg
£594.00
E-AB-F11100-1MG
About this Product
- SKU:
- E-AB-F11100
- Additional Names:
- T-cell surface glycoprotein CD8 alpha chain,CD8A,T-lymphocyte differentiation antigen T8/Leu-2,MAL
- Application:
- Depletion, Flow Cytometry
- Buffer:
- 0.2 uM PBS
- Clone:
- OKT-8
- Clonality:
- Monoclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- CD8a is a 32-34 kD type I glycoprotein. It forms a homodimer (CD8a/a) or heterodimer (CD8a/b) with CD8b. CD8, also known as T8 and Leu2, is a member of the immunoglobulin superfamily found on the majority of thymocytes, a subset of peripheral blood T cells, and NK cells (which express almost exclusively CD8a homodimers). CD8 acts as a co-receptor with MHC class I-restricted T cell receptors in antigen recognition and T cell activation and has been shown to play a role in thymic differentiation. Two domains in CD8a are important for function: the extracellular IgSF domain binds the A Alpha3 domain of MHC class I and the cytoplasmic CXCP motif binds the tyrosine kinase p56 Lck.
- Host:
- Mouse
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8[o]C Do not freeze.
- Supplier:
- Elabscience
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:p-af_le_purified_anti_human_cd8a_antibody_okt_8_e_ab_f11100-176595.html