AF/LE Purified Anti-Mouse CD103 Antibody[M290]
Product Sizes
50 ug
£198.00
E-AB-F10900-50UG
500 ug
£380.00
E-AB-F10900-500UG
1 mg
£594.00
E-AB-F10900-1MG
About this Product
- SKU:
- E-AB-F10900
- Additional Names:
- Integrin alpha-E,Itgae,Integrin alpha M290,CD103
- Application:
- Block/Inhibit/Neutralise, Flow Cytometry
- Buffer:
- 0.2 uM PBS
- Clone:
- M290
- Clonality:
- Monoclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- CD103 is a type I transmembrane glycoprotein known as A AlphaE integrin or Integrin A AlphaIEL chain. It belongs to the integrin family and is primarily found on intestinal intraepithelial lymphocytes (IEL). CD103 is also expressed on a subpopulation of lamina propria T cells, epithelial dendritic cells, lamina propria-derived dendritic cells, and a small subset of peripheral lymphocytes. T regulatory cells express high level of CD103. The CD103 expression on lymphocytes can be induced upon activation and TGF-B Beta stimulation. In association with integrin B Beta7, CD103 is expressed as A AlphaE/B Beta7 heterodimer. Mature CD103 protein can be cleaved into 2 chains, a 150 kD (C-terminal) chain and a 25 kD (N-terminal) chain, which remain linked by disulfide bonds. CD103 binds to E-cadherin and mediates homing of lymphocytes to the intestinal epithelium.
- Host:
- Rat
- Reactivities:
- Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8[o]C Do not freeze.
- Supplier:
- Elabscience
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:p-af_le_purified_anti_mouse_cd103_antibody_m290_e_ab_f10900-208948.html