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Antibodies

AF/LE Purified Anti-Mouse CD120b Antibody[TR75-54.7]

Product Sizes
50 ug
£220.00
E-AB-F10350-50UG
500 ug
£541.00
E-AB-F10350-500UG
1 mg
£755.00
E-AB-F10350-1MG
About this Product
SKU:
E-AB-F10350
Additional Names:
Tumor necrosis factor receptor superfamily member 1B,Tnfrsf1b,Tumor necrosis factor receptor 2,TNF-R2,TNF-RII,TNFR-II,p75,p80 TNF-alpha receptor,CD120b
Application:
Block/Inhibit/Neutralise, Flow Cytometry
Buffer:
0.2 uM PBS
Clone:
TR75-54.7
Clonality:
Monoclonal
Concentration:
0.5 mg/ml
Extra Details:
CD120b is a 75 kD type I transmembrane protein, also known as Tumor Necrosis Factor Receptor Type II (TNFRII) or p75. It is expressed on a variety of cells at low levels; the expression is upregulated upon activation. This receptor binds both TNF-A Alpha and LT-A Alpha (also known as TNF-B Beta). In association with TRAF1 and TRAF2, the receptor crosslinking induced by TNF-A Alpha or LT-A Alpha trimers is critical for signal transduction, leading to apoptosis, NF-kB activation, increased expression of proinflammatory genes, tumor necrosis, and cell differentiation depending on cell type and differentiation state.
Host:
Hamster
Reactivities:
Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
2-8[o]C Do not freeze.
Supplier:
Elabscience
Type:
Antibody: Monoclonal Antibody