AF/LE Purified Anti-Mouse CD122 Antibody[5H4]
Product Sizes
50 ug
£198.00
E-AB-F10290-50UG
500 ug
£380.00
E-AB-F10290-500UG
1 mg
£594.00
E-AB-F10290-1MG
About this Product
- SKU:
- E-AB-F10290
- Additional Names:
- Interleukin-2 receptor subunit beta,Il2rb,IL-2 receptor subunit beta, IL-2R subunit beta,IL-2RB,High affinity IL-2 receptor subunit beta,p70-75,CD122
- Application:
- Flow Cytometry
- Buffer:
- 0.2 uM PBS
- Clone:
- 5H4
- Clonality:
- Monoclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- CD122 is a 70-75 kD IL-2 receptor B Beta chain also known as IL-2RB Beta, which is also shared by the IL-15 receptor. It is constitutively expressed by NK cells and at lower levels by T cells, B cells, monocytes, and macrophages. The IL-2RB Beta chain can combine with either the common G Gamma subunit (G Gammac, CD132) alone or with the G Gammac subunit and the IL-2RA Alpha subunit (CD25) to generate intermediate or high affinity IL-2 receptor complexes, respectively. CD122 expression levels can be upregulated by activation. The 5H4 antibody does not block IL-2 binding to the IL-2 receptor. CD122 is expressed on murine, but not human, CD8+ Tregs involved in the maintenance of T cell homeostasis.
- Host:
- Rat
- Reactivities:
- Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8[o]C Do not freeze.
- Supplier:
- Elabscience
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:p-af_le_purified_anti_mouse_cd122_antibody_5h4_e_ab_f10290-208941.html