AF/LE Purified Anti-Mouse CD54 Antibody[YN1/1.7.4]
Product Sizes
50 ug
£198.00
E-AB-F10180-50UG
500 ug
£380.00
E-AB-F10180-500UG
1 mg
£594.00
E-AB-F10180-1MG
About this Product
- SKU:
- E-AB-F10180
- Additional Names:
- Intercellular adhesion molecule 1,Icam1,MALA-2,MyD10,CD54,Icam-1
- Application:
- Flow Cytometry
- Buffer:
- 0.2 uM PBS
- Clone:
- YN1/1.7.4
- Clonality:
- Monoclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- CD54 is a 90 kD immunoglobulin superfamily member also known as ICAM-1 and Ly-47. It is expressed on activated endothelial cells, high endothelial venules (HEV), T and B cells, monocytes/ macrophages, granulocytes, and dendritic cells. CD54 is an important intracellular adhesion molecule that participates in T cell-T cell, T cell-B cell, and T cell-target cell interactions via binding of LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18). CD54 has also been shown to be involved in lymphocyte trafficking, making it an important molecule in many immune reactions and inflammation. CD54 is also a receptor for rhinovirus. The YN1/1.7.4 antibody has been reported to block binding of mouse CD54 to LFA-1 and Mac-1, inhibit cell-cell adhesion, and function in antigen presentation to T cells and leukocyte migration to inflammatory tissues.
- Host:
- Rat
- Reactivities:
- Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8[o]C Do not freeze.
- Supplier:
- Elabscience
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:p-af_le_purified_anti_mouse_cd54_antibody_yn1_1.7.4_e_ab_f10180-208936.html