Nerve growth factor receptor, extracellular domain (NGFR/p75ECD), Human, Rapid[TM] ELISA assay-2 Plate Kit
Product Sizes
2 Plate Kit
£690.00
BEK-2239-2P-2PLATEKIT
About this Product
- SKU:
- BEK-2239-2P
- Additional Names:
- Low-affinity nerve growth factor receptor; NGF receptor; Gp80-LNGFR; p75 ICD; Low affinity neurotrophin receptor p75NTR; Tumor necrosis factor receptor superfamily member 16; CD271; NGFR; TNFRSF16; NGFR/p75ECD; p75ECD;
- Application:
- ELISA
- Extra Details:
- The Biosensis NGFR/p75ECD RapidTM enzyme-linked immunosorbent assay (ELISA) Kit s a sandwich ELISA that allows the quantification of the extracellular domain (ECD) of human p75 neurotrophin receptor in less than 4 hours in urine only if used as directed. Please refer to the kit protocol for specific use instructions for urine application.
This ELISA kit consists of a pre-coated mouse monoclonal anti-p75ECD capture antibody, a biotinylated mouse monoclonal anti-p75ECD detection antibody and horseradish peroxidase (HRP)-conjugated streptavidin. The addition of a substrate (3,3',5,5'-tetramethylbenzidine, TMB) yields a colored reaction product which is directly proportional to the concentration of p75ECD present in samples and protein standards. A human p75ECD positive control (QC sample) is provided to assure consistent assay performance.
This NGFR/p75ECD ELISA kit employs a recombinant human p75ECD-Fc chimera. While there is a current lack of a commercially available, true human p75ECD standard, this ELISA kit allows quantification of human p75ECD as p75ECD-Fc human equivalents. Please note that the antibodies used in this ELISA do not cross-react with mouse p75ECD.
Note: For research use only. Not for diagnostic and clinical purposes.Receive a 20% discount on the Biosensis Creatinine (Urinary) Colorimetric Assay Kit (CRE-001) if purchased together with this ELISA kit in one transaction. To receive a quote, contact us at sales@biosensis.com.
- Host:
- Human
- References:
- The following references give a general background on the suitability of p75<sup>ECD</sup> as a biomarker for ALS disease progression.<br><br>Shepheard et al. (2017) Neurology 2017 Feb 22. doi: 10.1212/WNL.0000000000003741. [Epub ahead of print].<br><br>Shepheard et al. (2014) PLoS ONE 9(1): e87398. doi:10.1371/journal.pone.0087398.<br><br>DiStefano & Johnson (1988) Proc Natl Acad Sci USA 85: 270-274.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8°C (on cold packs)
- Supplier:
- Biosensis