Human HER2 / ErbB2 ELISA Kit
Product Sizes
96 wells
£711.00
ARG83043-96WELLS
About this Product
- SKU:
- ARG83043
- Additional Names:
- ERBB2, Erb B2 Receptor Tyrosine Kinase 2, HER2, NEU, C ERB 2, C ERB2, HER 2, CD340, NGL, V Erb B2 Avian Erythroblastic Leukemia Viral Oncogene Homolog 2, Tyrosine Kinase Type Cell Surface Receptor HER2, Neuro / Glioblastoma Derived Oncogene Homolog, Human Epidermal Growth Factor Receptor 2, Receptor Tyrosine Protein Kinase ErbB 2, Metastatic Lymph Node Gene 19 Protein, Proto Oncogene C ErbB 2, Proto Oncogene Neu, P185(ErbB2), EC 2.7.10.1, MLN 19, MLN 19, V Erb B2 Avian Erythroblastic Leukemia Viral Oncogene Homolog 2 (Neuro / Glioblastoma Derived Oncogene Homolog), V Erb B2 Erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro / Glioblastoma Derived Oncogene Homolog, V Erb B2 Avian Erythroblastic Leukemia Viral Oncoprotein 2, Neuroblastoma / Glioblastoma Derived Oncogene Homolog, Metastatic Lymph Node Gene 19, C Erb B2 / Neu Protein, CD340 Antigen, HER 2 / Neu, Herstatin, P185erbB2, EC 2.7.10, VSCN2, MLN19, TKR1
- Application:
- ELISA
- CE/IVD:
- RUO
- Conjugate:
- HRP
- Extra Details:
- This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase. Allelic variations at amino acid positions 654 and 655 of isoform a (positions 624 and 625 of isoform b) have been reported, with the most common allele, Ile654/Ile655, shown here. Amplification and/or overexpression of this gene has been reported in numerous cancers, including breast and ovarian tumors. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized. [provided by RefSeq, Jul 2008]
- Physical State:
- Ascites, Cell Culture Supernatant, Plasma, Serum, Urine
- Sensitivity:
- 23.44 pg/ml
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8[o]C
- Supplier:
- Arigo Biolaboratories
- Type:
- Assay Kits: ELISAs
