Human CD274 / PD L1 ELISA Kit
Product Sizes
96 wells
ARG83029-96WELLS
About this Product
- SKU:
- ARG83029
- Additional Names:
- CD274, CD274 Molecule, PDL1, B7H, PDL1, Programmed Cell Death 1 Ligand 1, CD274 Antigen , B7 Homolog 1, PDCD1LG1, B7 H1, B7 H, PDCD1 Ligand 1, PDCD1L1, HPD-L1, Programmed Death Ligand 1
- Application:
- ELISA
- CE/IVD:
- RUO
- Conjugate:
- HRP
- Extra Details:
- This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein is a type I transmembrane protein that has immunoglobulin V-like and C-like domains. Interaction of this ligand with its receptor inhibits T-cell activation and cytokine production. During infection or inflammation of normal tissue, this interaction is important for preventing autoimmunity by maintaining homeostasis of the immune response. In tumor microenvironments, this interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation. Expression of this gene in tumor cells is considered to be prognostic in many types of human malignancies, including colon cancer and renal cell carcinoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
- Immunogen:
- CD274
- Physical State:
- Ascites, Cell Culture Supernatant, Plasma, Serum, Urine
- Reactivities:
- Human
- Sensitivity:
- 78 pg/ml
- Shipping Conditions:
- Blue Ice
- Specificity:
- Not cross-reacts with: Human IL2, IL4, IL6, IL10,TNF alpha, TNF beta,PD1.Mouse IL2, IL4, IL5, IL6, IL8, IL10, IL12, PD1,PDL1.Rat IL2, PD1,PDL1.
- Storage Conditions:
- 2-8[o]C
- Supplier:
- Arigo Biolaboratories
- Type:
- Assay Kits: ELISAs
- Manufacturer's Data Sheet:ARG83029.html
