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Proteins and Peptides

Human Activin A recombinant protein (Active) (Tag free)

Product Sizes
20 ug
£433.00
ARG70474-20UG
100 ug
£818.00
ARG70474-100UG
Academic Pricing
Please contact us for academic pricing.
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About this Product
SKU:
ARG70474
Additional Names:
Erythroid differentiation protein; Activin beta-A chain; FRP; EDF; Inhibin beta A chain
Application:
SDS-PAGE
Buffer:
PBS (pH 7.4)
CE/IVD:
RUO
Extra Details:
The inhibin beta A subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta A subunit forms a homodimer, activin A, and also joins with a beta B subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion. Finally, it has been shown that the beta A subunit mRNA is identical to the erythroid differentiation factor subunit mRNA and that only one gene for this mRNA exists in the human genome. [provided by RefSeq, Jul 2008]
Purity:
>95%
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C
Supplier:
Arigo Biolaboratories
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins