Human CD255 / TWEAK recombinant protein (Active) (His-tagged, C-ter)
Product Sizes
20 ug
£433.00
ARG70392-20UG
100 ug
£818.00
ARG70392-100UG
About this Product
- SKU:
- ARG70392
- Additional Names:
- TNFSF12; TNF Superfamily Member 12; TWEAK; DR3LG; APO3L; Tumor Necrosis Factor (Ligand) Superfamily, Member 12; Tumor Necrosis Factor Ligand Superfamily Member 12; APO3 Ligand; Tumor Necrosis Factor Superfamily Member 12; TNF-Related WEAK Inducer Of Apoptosis; TNF-Related Weak Inducer Of Apoptosis; Tumor Necrosis Factor Ligand 4A; APO3/DR3 Ligand; TNLG4A
- Application:
- SDS-PAGE
- Buffer:
- PBS (pH 8.0)
- CE/IVD:
- RUO
- Extra Details:
- The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is a ligand for the FN14/TWEAKR receptor. This cytokine has overlapping signaling functions with TNF, but displays a much wider tissue distribution. This cytokine, which exists in both membrane-bound and secreted forms, can induce apoptosis via multiple pathways of cell death in a cell type-specific manner. This cytokine is also found to promote proliferation and migration of endothelial cells, and thus acts as a regulator of angiogenesis. Alternative splicing results in multiple transcript variants. Some transcripts skip the last exon of this gene and continue into the second exon of the neighboring TNFSF13 gene; such read-through transcripts are contained in GeneID 407977, TNFSF12-TNFSF13.
- Purity:
- >98% (by SDS-PAGE)
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C
- Supplier:
- Arigo Biolaboratories
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
