Human FGFR2 recombinant protein (Active) (ECD) (Fc-His-tagged, C-ter)
Product Sizes
100 ug
£764.00
ARG70331-100UG
About this Product
- SKU:
- ARG70331
- Additional Names:
- CD antigen CD332; BEK; Keratinocyte growth factor receptor; K-SAM; ECT1; FGFR-2; KGFR; JWS; TK14; CFD1; BBDS; TK25; K-sam; CEK3; Fibroblast growth factor receptor 2; EC 2.7.10.1; CD332; BFR-1
- Application:
- Cell-based/Functional Assay, SDS-PAGE
- Buffer:
- PBS (pH 7.4)
- CE/IVD:
- RUO
- Extra Details:
- The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member is a high-affinity receptor for acidic, basic and/or keratinocyte growth factor, depending on the isoform. Mutations in this gene are associated with Crouzon syndrome, Pfeiffer syndrome, Craniosynostosis, Apert syndrome, Jackson-Weiss syndrome, Beare-Stevenson cutis gyrata syndrome, Saethre-Chotzen syndrome, and syndromic craniosynostosis. Multiple alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jan 2009]
- Purity:
- >97%
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C
- Supplier:
- Arigo Biolaboratories
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Enzymes
