Human CD140b / PDGFRB recombinant protein (ECD) (Fc-His-tagged, C-ter)
Product Sizes
100 ug
£711.00
ARG70254-100UG
About this Product
- SKU:
- ARG70254
- Additional Names:
- PDGF-R-beta; IBGC4; CD antigen CD140b; Platelet-derived growth factor receptor beta; CD140B; PDGFR; PDGFR-1; Beta platelet-derived growth factor receptor; PDGFR1; Platelet-derived growth factor receptor 1; PDGFR-beta; CD140 antigen-like family member B; IMF1; EC 2.7.10.1; JTK12; Beta-type platelet-derived growth factor receptor
- Application:
- Cell-based/Functional Assay, SDS-PAGE
- Buffer:
- PBS (pH 7.4)
- CE/IVD:
- RUO
- Extra Details:
- The protein encoded by this gene is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer (PDGFB or PDGFD) or a heterodimer (PDGFA and PDGFB). This gene is essential for normal development of the cardiovascular system and aids in rearrangement of the actin cytoskeleton. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the ETV6 gene, results in chronic myeloproliferative disorder with eosinophilia. [provided by RefSeq, Aug 2017]
- Purity:
- >90%
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C
- Supplier:
- Arigo Biolaboratories
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Enzymes
