Human ERBB4 / HER4 recombinant protein (ECD) (Fc-His-tagged, C-ter)
Product Sizes
50 ug
£604.00
ARG70251-50UG
About this Product
- SKU:
- ARG70251
- Additional Names:
- E4ICD; s80HER4; Proto-oncogene-like protein c-ErbB-4; p180erbB4; Tyrosine kinase-type cell surface receptor HER4; Receptor tyrosine-protein kinase erbB-4; 4ICD; EC 2.7.10.1; ALS19; HER4
- Application:
- Cell-based/Functional Assay, SDS-PAGE
- Buffer:
- PBS (pH 7.4)
- CE/IVD:
- RUO
- Extra Details:
- This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008]
- Purity:
- >97%
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C
- Supplier:
- Arigo Biolaboratories
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Enzymes
