Human GDNF recombinant protein (Active) (His-tagged, C-ter)
Product Sizes
20 ug
£433.00
ARG70143-20UG
100 ug
£818.00
ARG70143-100UG
About this Product
- SKU:
- ARG70143
- Additional Names:
- ATF; Astrocyte-derived trophic factor; HSCR3; hGDNF; Glial cell line-derived neurotrophic factor; HFB1-GDNF; ATF1; ATF2
- Application:
- SDS-PAGE
- Buffer:
- 20 mM sodium citrate and 0.2 M NaCl (pH 3.5)
- CE/IVD:
- RUO
- Extra Details:
- This gene encodes a highly conserved neurotrophic factor. The recombinant form of this protein was shown to promote the survival and differentiation of dopaminergic neurons in culture, and was able to prevent apoptosis of motor neurons induced by axotomy. The encoded protein is processed to a mature secreted form that exists as a homodimer. The mature form of the protein is a ligand for the product of the RET (rearranged during transfection) protooncogene. Multiple transcript variants encoding different isoforms have been found for this gene. Mutations in this gene may be associated with Hirschsprung disease. [provided by RefSeq, Jun 2010]
- Purity:
- >95% (by SDS-PAGE)
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C
- Supplier:
- Arigo Biolaboratories
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins