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Proteins and Peptides

Human GDNF recombinant protein (Active) (His-tagged, C-ter)

Product Sizes
20 ug
£433.00
ARG70143-20UG
100 ug
£818.00
ARG70143-100UG
Academic Pricing
Please contact us for academic pricing.
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About this Product
SKU:
ARG70143
Additional Names:
ATF; Astrocyte-derived trophic factor; HSCR3; hGDNF; Glial cell line-derived neurotrophic factor; HFB1-GDNF; ATF1; ATF2
Application:
SDS-PAGE
Buffer:
20 mM sodium citrate and 0.2 M NaCl (pH 3.5)
CE/IVD:
RUO
Extra Details:
This gene encodes a highly conserved neurotrophic factor. The recombinant form of this protein was shown to promote the survival and differentiation of dopaminergic neurons in culture, and was able to prevent apoptosis of motor neurons induced by axotomy. The encoded protein is processed to a mature secreted form that exists as a homodimer. The mature form of the protein is a ligand for the product of the RET (rearranged during transfection) protooncogene. Multiple transcript variants encoding different isoforms have been found for this gene. Mutations in this gene may be associated with Hirschsprung disease. [provided by RefSeq, Jun 2010]
Purity:
>95% (by SDS-PAGE)
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C
Supplier:
Arigo Biolaboratories
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins