Human CD137L / TNFSF9 recombinant protein (Active) (His-tagged, C-ter)
Product Sizes
20 ug
£433.00
ARG70103-20UG
100 ug
£818.00
ARG70103-100UG
About this Product
- SKU:
- ARG70103
- Additional Names:
- 4-1BBL; 4-1BB ligand; Tumor necrosis factor ligand superfamily member 9; 4-1BB-L; CD137L
- Application:
- SDS-PAGE
- Buffer:
- PBS (pH 7.4)
- CE/IVD:
- RUO
- Extra Details:
- The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This transmembrane cytokine is a bidirectional signal transducer that acts as a ligand for TNFRSF9/4-1BB, which is a costimulatory receptor molecule in T lymphocytes. This cytokine and its receptor are involved in the antigen presentation process and in the generation of cytotoxic T cells. The receptor TNFRSF9/4-1BB is absent from resting T lymphocytes but rapidly expressed upon antigenic stimulation. The ligand encoded by this gene, TNFSF9/4-1BBL, has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine has also been shown to be required for the optimal CD8 responses in CD8 T cells. This cytokine is expressed in carcinoma cell lines, and is thought to be involved in T cell-tumor cell interaction.[provided by RefSeq, Oct 2008]
- Purity:
- >95% (by SDS-PAGE)
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C
- Supplier:
- Arigo Biolaboratories
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
