anti-CD172a / SIRP alpha antibody
Product Sizes
50 ug
£582.00
ARG54417-50UG
About this Product
- SKU:
- ARG54417
- Additional Names:
- CD172A; p84; SHPS1; SHPS-1; CD172 antigen-like family member A; Sirp-alpha-3; Sirp-alpha-1; BIT; MYD-1; MFR; Bit; PTPNS1; CD antigen CD172a; Inhibitory receptor SHPS-1; SIRP; MyD-1 antigen; Sirp-alpha-2; Tyrosine-protein phosphatase non-receptor type substrate 1; Signal-regulatory protein alpha-1; Signal-regulatory protein alpha-2; Signal-regulatory protein alpha-3; Macrophage fusion receptor; Brain Ig-like molecule with tyrosine-based activation motifs; P84; SHP substrate 1
- Application:
- Western Blot
- Buffer:
- PBS (pH 7.4) and 0.02% Sodium azide
- CE/IVD:
- RUO
- Clonality:
- Polyclonal
- Extra Details:
- Protein tyrosine phosphatases (PTPases), such as SHP-1 and SHP-2, are critical regulators in the intracellular signaling pathways that result in cell responses such as mitosis, differentiation, migration, survival, transformation or death. SHP-2 is a signal transducer for several receptor tyrosine kinases and cytokine receptors. A novel SHP-2 associated glycoprotein was recently cloned from human, rat, mouse, and cattle by several laboratories and was designated SIRPA Alpha, SHPS-1, and MyD-1. SIRPA Alpha/SHPS-1 is a new gene family containing at least fifteen members. SIRPA Alpha/SHPS-1 is a substrate of manyactivated tyrosine kinases such as insulin receptor, EGFR, PDGFR, and src, and is a specific docking protein for SHP-2. SIRPA Alpha/SHPS-1 has regulatory effects on cellular responses induced by serum,growth factors, insulin, oncogenes, and cell adhesion and plays a general role in different physiological and pathological processes.
- Host:
- Rabbit
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Bovine, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C
- Supplier:
- Arigo Biolaboratories
- Type:
- Antibody: Polyclonal Antibody