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Antibodies

anti-CD261 / TRAIL R1 antibody

Product Sizes
50 ug
£582.00
ARG54397-50UG
Academic Pricing
Please contact us for academic pricing.
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About this Product
SKU:
ARG54397
Additional Names:
TNF-related apoptosis-inducing ligand receptor 1; CD antigen CD261; TRAILR-1; DR4; Tumor necrosis factor receptor superfamily member 10A; CD261; Death receptor 4; APO2; TRAIL receptor 1; TRAIL-R1; TRAILR1
Application:
Immunocytochemistry, Immunofluorescence, Western Blot
Buffer:
PBS (pH 7.4) and 0.02% Sodium azide
CE/IVD:
RUO
Clonality:
Polyclonal
Extra Details:
Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family through their death domain-containing receptors, TNFR1 and Fas. Another cell death receptor was recently identified and designated DR4. The ligand for DR4 has been designated TRAIL and is a new member of the TNF family. Therefore, DR4 is also called TRAIL receptor-1. DR4 is expressed in most human tissues including spleen, peripheral blood, small intestine, and thymus. Like TNFR1, Fas and DR3, DR4 mediates TRAIL-induced apoptosis and NF-B activation in many tissues and cells.
Host:
Rabbit
Isotype:
IgG
Purification:
Affinity Purified
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C
Supplier:
Arigo Biolaboratories
Type:
Antibody: Polyclonal Antibody