anti-beta III Tubulin antibody [AA10]
Product Sizes
50 ul
£572.00
ARG52460-50UL
About this Product
- SKU:
- ARG52460
- Additional Names:
- CDCBM1; Tubulin beta-4 chain; Tubulin beta-3 chain; CFEOM3A; Tubulin beta-III; TUBB4; CDCBM; CFEOM3; FEOM3; beta-4
- Application:
- Immunohistochemistry, Western Blot
- Buffer:
- 10 mM HEPES (pH 7.5), 150 mM NaCl, 0.1 mg/ml BSA and 50% Glycerol
- CE/IVD:
- RUO
- Clone:
- AA10
- Clonality:
- Monoclonal
- Extra Details:
- Tubulin is the major constituent of microtubules, existing as a heterodimer of the A Alpha and B Beta subunits. The beta III isoform of Tubulin is found almost exclusively in neuronal processes of adult tissues and is therefore an excellent marker for neurons. Neuron specific, posttranslational modifications within the C-terminal domain of beta III Tubulin have been shown to be developmentally regulated suggesting that they may serve to modulate the interaction of Tubulin with microtubule associated proteins (Lee et al., 1990). Additionally, beta III Tubulin has been found to be highly expressed in cancer cells such as small cell lung cancer, large cell neuroendocrine carcinoma and adenocarcinomas and is correlated with an increasing histological degree of malignancy (Katsetos et al., 2003)
- Host:
- Mouse
- Isotype:
- IgG
- Purification:
- Protein G Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C
- Supplier:
- Arigo Biolaboratories
- Type:
- Antibody: Monoclonal Antibody
