anti-eEF1A2 phospho (Ser358) antibody
Product Sizes
50 ul
£572.00
ARG52271-50UL
About this Product
- SKU:
- ARG52271
- Additional Names:
- EF1A; Eukaryotic elongation factor 1 A-2; eEF1A-2; Elongation factor 1-alpha 2; STN; EIEE33; STNL; Statin-S1; HS1; EEF1AL; EF-1-alpha-2; MRD38
- Application:
- Western Blot
- Buffer:
- 10 mM HEPES (pH 7.5), 150 mM NaCl, 0.1 mg/ml BSA and 50% Glycerol
- CE/IVD:
- RUO
- Clonality:
- Polyclonal
- Extra Details:
- Eukaryotic Elongation Factor eEF1A exists in two variant forms, eEF1A1 and eEF1A2. While eEF1A1 is almost ubiquitously expressed in humans, eEF1A2 is predominantly found in heart, brain, and skeletal muscle (Knudsen et al., 1993). Expression of eEF1A2 may have a role in ovarian cancer, as its expression is drastically increased in human ovarian tumors (Anand et al., 2002). Due to differences in structural models between the two isoforms, eEF1A1 and eEF1A2 likely have variant-specific phosphorylation sites (Soares et al., 2009). Ribosome-associated JNK phosphorylates Ser358 on eEF1A2 to promote degradation of newly synthesized polypeptides by the proteasome (Gandin et al., 2013).
- Host:
- Rabbit
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Amphibian, Avian, Human, Non-human Primate, Rat, Sheep
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C
- Supplier:
- Arigo Biolaboratories
- Type:
- Antibody: Polyclonal Antibody
