anti-Insulin antibody [IRDN/794]
Product Sizes
50 ug
£593.00
ARG43786-50UG
About this Product
- SKU:
- ARG43786
- Additional Names:
- IDDM; IDDM2; IDDM1; ILPR; MODY10; Insulin; IRDN
- Application:
- IHC-Paraffin
- Buffer:
- PBS (pH 7.4), 0.05% Sodium azide and 0.1 mg/ml BSA.
- CE/IVD:
- RUO
- Clone:
- IRDN/794
- Clonality:
- Monoclonal
- Concentration:
- 0.2 mg/ml
- Extra Details:
- After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]
- Host:
- Mouse
- Isotype:
- IgG1, kappa
- Purification:
- Protein G Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C
- Supplier:
- Arigo Biolaboratories
- Type:
- Antibody: Monoclonal Antibody