anti-SARS-CoV-2 ORF9b antibody
Product Sizes
100 ug
£818.00
ARG43724-100UG
About this Product
- SKU:
- ARG43724
- Additional Names:
- Accessory protein 9b, ORF-9b, Protein 9b
- Application:
- ELISA, Western Blot
- Buffer:
- PBS and 0.02% Sodium azide.
- CE/IVD:
- RUO
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- Coronavirus disease 2019 (COVID-19), formerly known as 2019-nCoV acute respiratory disease, is an infectious disease caused by SARS-CoV-2, a virus closely related to the SARS virus. The disease is the cause of the 2019-20 coronavirus outbreak. The structure of 2019-nCoV consists of the following: a spike protein (S), hemagglutinin-esterease dimer (HE), a membrane glycoprotein (M), an envelope protein (E) a nucleoclapid protein (N) and RNA. ORF9b plays a role in the inhibition of host innate immune response by targeting the mitochondrial-associated adapter MAVS. Mechanistically, it usurps the E3 ligase ITCH to trigger the degradation of MAVS, TRAF3, and TRAF6. In addition, it causes mitochondrial elongation by triggering ubiquitination and proteasomal degradation of dynamin-like protein 1/DNM1L.
- Host:
- Rabbit
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C
- Supplier:
- Arigo Biolaboratories
- Type:
- Antibody: Polyclonal Antibody
