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Antibodies

anti-APC antibody

Product Sizes
100 ul
£593.00
ARG41590-100UL
Academic Pricing
Please contact us for academic pricing.
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About this Product
SKU:
ARG41590
Additional Names:
GS; DP2.5; DP3; DP2; Adenomatous polyposis coli protein; BTPS2; PPP1R46; Protein APC; Deleted in polyposis 2.5
Application:
IHC-Paraffin, Immunocytochemistry, Immunofluorescence
Buffer:
PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
CE/IVD:
RUO
Clonality:
Polyclonal
Extra Details:
This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product. [provided by RefSeq, Jul 2008]
Host:
Rabbit
Isotype:
IgG
Purification:
Affinity Purified
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C
Supplier:
Arigo Biolaboratories
Type:
Antibody: Polyclonal Antibody