Biotinylated Human TFPI Protein, His Tag, ultra sensitivity (primary amine labeling)
Product Sizes
25 ug
£295.00
TFI-H8226-25UG
200 ug
£1,295.00
TFI-H8226-200UG
About this Product
- SKU:
- TFI-H8226
- Additional Names:
- EPI|LACI|TFI|TFPI|TFPI1
- Buffer:
- PBS, pH7.4
- Extra Details:
- Tissue factor pathway inhibitor (TFPI) is also known as Extrinsic pathway inhibitor (EPI), Lipoprotein - associated coagulation inhibitor (LACI), is a plasma proteinase inhibitor synthesized by vascular endothelial cells and part of it is associated with glycosaminoglycans of these cells. TFPI is a single-chain polypeptide which can reversibly inhibit Factor Xa (Xa) and Thrombin (Factor IIa). TFPI is a secreted protein with a N-terminal acidic region, three Kunitz (K) domains separated with by two linker regions, and a C-terminal basic region. The first K domain inhibits coagulation factor VIIa complexed to tissue factor (TF); The second K domain inhibits factor Xa; The third K domain binds to heparin; The C-terminal basic region may have several functions. For example, it plays an important role in binding of TFPI to cell surfaces.
- Molecular Weight:
- 30.0 kDa
- Physical State:
- Powder
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Conjugated Protein