Biotinylated Human / Cynomolgus / Rhesus macaque ROR1 Protein, Fc,Avitag[TM]
Product Sizes
25 ug
£365.00
RO1-H82F4-25UG
200 ug
£1,565.00
RO1-H82F4-200UG
About this Product
- SKU:
- RO1-H82F4
- Additional Names:
- NTRKR1|ROR1
- Buffer:
- 50 mM Tris, 100 mM Glycine, 150 mM NaCl, pH7.5
- Extra Details:
- Tyrosine-protein kinase transmembrane receptor ROR1 is also known as Neurotrophic tyrosine kinase, receptor-related 1 (NTRKR1), which belongs to the protein kinase superfamily or tyr protein kinase family or ROR subfamily. ROR1 contains 1 FZ (frizzled) domain, 1 Ig-like C2-type (immunoglobulin-like) domain, 1 kringle domain, 1 protein kinase domain. ROR1 is expressed at high levels during early embryonic development. The expression levels drop strongly around day 16 and there are only very low levels in adult tissues. Isoform Short is strongly expressed in fetal and adult CNS and in a variety of human cancers, including those originating from CNS or PNS neuroectoderm. ROR1 could interact with casein kinase 1 epsilon (CK1E Epsilon) to activate phosphoinositide 3-kinase-mediated AKT phosphorylation and cAMP-response-element-binding protein (CREB), which was associated with enhanced tumor-cell growth.
- Molecular Weight:
- 70.1 kDa
- Physical State:
- Powder
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Enzymes