Human LGR5 / GPR49 protein, His Tag
Product Sizes
100 ug
£377.00
LG5-H52H3-100UG
1 mg
£2,753.00
LG5-H52H3-1MG
About this Product
- SKU:
- LG5-H52H3
- Additional Names:
- GPR49|GPR67|G-protein coupled receptor 49|G-protein coupled receptor 67|G-protein coupled receptor HG38|Leucine-rich repeat-containing G-protein coupled receptor 5|LGR5
- Buffer:
- PBS, pH7.4
- Extra Details:
- LGR5 (also known as GPR49) is a seven-transmembrane protein of the class A Rhodopsin-like family of GPCRs. LGR5 and LGR4 bind the R-spondins with high affinity and mediate the potentiation of Wnt/B Beta-catenin signaling by enhancing Wnt-induced LRP6 phosphorylation. The LGR5/RSPO complex could promote Wnt signalling via the neutralization of two transmembrane E3 ligases, RNF43 and ZNRF3.
- Molecular Weight:
- 62.0 kDa
- Physical State:
- Powder
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins