CD27L [Biotinylated] : CD27 Inhibitor Screening ELISA Kit
Product Sizes
96 tests
£671.00
EP-121-96TESTS
About this Product
- SKU:
- EP-121
- Application:
- ELISA
- Extra Details:
- Cluster of Differentiation 70 (CD70) is also known as CD27 ligand (CD27L / CD27LG), TNFSF7, TNFSF7G, is a type II transmembrane glycoprotein belonging to the TNF superfamily (TNFSF) and is a surface antigen found on activated T-and B-lymphocytes and mature dendritic cells. Binding of CD70 to its receptor CD27 induces in priming, effector functions, differentiation and memory formation of T-cells, and thus is invloved in the biological processes including T-cell activation, the proliferation of costimulated T-cells, as well as the generation of cytolytic T-cells. CD70 on T cells provides costimulatory signals that are required for T cell proliferation, clonal expansion and the promotion of effector T cell formation. CD70 on mouse B cell has been shown to inhibit terminal differentiation of activated B cells into plasma cells and enhances commitment to memory B cell responses. CD70 induces proliferation and IFNG Gamma production, on NK cells.
- Physical State:
- Solid
- Reactivities:
- Human
- Shipping Conditions:
- Ambient
- Storage Conditions:
- 2-8[o]C
- Supplier:
- ACRO Biosystems
- Type:
- Assay Kits: ELISAs