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Proteins and Peptides

Alexa Fluor[TM] 555-Labeled Human CD27 Ligand / CD70 Protein, His TagStar Staining

Product Sizes
25 ug
£436.00
CDL-HA245-25UG
200 ug
£2,695.00
CDL-HA245-200UG
About this Product
SKU:
CDL-HA245
Buffer:
PBS, pH7.4
Extra Details:
Cluster of Differentiation 70 (CD70) is also known as CD27 ligand (CD27L / CD27LG), TNFSF7, TNFSF7G, is a type II transmembrane glycoprotein belonging to the TNF superfamily (TNFSF) and is a surface antigen found on activated T-and B-lymphocytes and mature dendritic cells. Binding of CD70 to its receptor CD27 induces in priming, effector functions, differentiation and memory formation of T-cells, and thus is invloved in the biological processes including T-cell activation, the proliferation of costimulated T-cells, as well as the generation of cytolytic T-cells. CD70 on T cells provides costimulatory signals that are required for T cell proliferation, clonal expansion and the promotion of effector T cell formation. CD70 on mouse B cell has been shown to inhibit terminal differentiation of activated B cells into plasma cells and enhances commitment to memory B cell responses. CD70 induces proliferation and IFNG Gamma production, on NK cells.
Molecular Weight:
64.2 kDa
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles. Protect from light.
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins