Human B7-H2 / ICOSLG Protein, His Tag
Product Sizes
200 ug
£283.00
B72-H5221-200UG
1 mg
£1,236.00
B72-H5221-1MG
About this Product
- SKU:
- B72-H5221
- Additional Names:
- B7H2|B7-H2|B7RP1|B7RP-1|CD275|GL50|ICOS ligand|ICOSL|ICOS-L|ICOSLG|LICOS
- Buffer:
- PBS, pH7.4
- Extra Details:
- ICOS ligand (ICOSLG) is also known as B7 homolog 2 (B7-H2), B7-related protein 1 (B7RP-1) and CD antigen CD275, which belongs to the immunoglobulin superfamily and BTN/MOG family. ICOSLG contains one Ig-like C2-type (immunoglobulin-like) domain and one Ig-like V-type (immunoglobulin-like) domain. Isoform 1 is widely expressed, while isoform 2 is detected only in lymph nodes, leukocytes and spleen. B7-H2 is ligand for the T-cell-specific cell surface receptor ICOS. B7-H2 acts as a costimulatory signal for T-cell proliferation and cytokine secretion and induces also B-cell proliferation and differentiation into plasma cells. B7-H2 could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function.
- Molecular Weight:
- 27.8 kDa
- Physical State:
- Powder
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins