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TR-FRET

Discover the TR-FRET range from 2BScientific.

More recent advancements in molecular biology have resulted in remarkable advancements that have revolutionised our understanding of life's intricacies. These breakthroughs have far-reaching implications, spanning from medical breakthroughs to ecological insights. A spear heading example of this is precision medicine and its advances in molecular biology enable personalised medical treatments based on a patient's genetic makeup. This includes tailoring drug regimens, predicting disease susceptibility, and identifying optimal therapies paving the way for further novel applications such as the CRISPR/Cas9 gene editing system which has revolutionised the ability to precisely modify genomes. Such technology has applications in research, but also holds potential for treating genetic disorders and developing personalised medicine.

Assay Kits for TR-FRET:

Using assay kits simplifies the experimental process by providing all necessary components in a single package. This convenience saves time and effort in procuring and preparing individual reagents. Additionally, these kits offer standardised protocols and optimised reagents, ensuring consistency and reliability across experiments.

Assay Kits by Reactivity

Human

Mouse

Rats

Buffers and ConsumablesBuffers & General Consumables: 

Buffers play a critical role in TR-FRET assays by maintaining the required pH, ionic strength, and environmental conditions. They create an ideal environment for accurate measurements and help prevent non-specific binding of molecules. This ensures the specificity and precision of TR-FRET results.

Buffers by Application

Block / Inhibit / Neutralise

Detection / Quantitation

Conjugated ProteinsConjugated Proteins: 

Conjugated proteins, labelled with fluorescent or luminescent markers, enable precise and specific detection of protein-protein interactions or binding events. Their use enhances the sensitivity of TR-FRET assays, as fluorescence is emitted only when the labels are in close proximity. This real-time monitoring capability is invaluable for studying dynamic molecular processes.

Conjugated Proteins

Acceptor - Labelled Streptavidin

Europium - Labelled Streptavidin

Tagged AntibodiesTagged Secondary Antibodies:

Tagged secondary antibodies, labelled with fluorescent or luminescent tags, provide versatility in TR-FRET assays. They can selectively bind to target molecules, allowing researchers to develop assays for a wide range of biomolecules. This versatility enables the study of various biological interactions, localisation within samples, and quantitative analysis, making TR-FRET assays adaptable to diverse research needs.

Assay Kits by Reactivity

Human

Mouse

Rabbit


BioAuxilium

BioAuxilium LogoBioAuxilium offers a diverse array of TR-FRET products, and are highly skilled in designing, developing, and producing assay kits and reagents for popular technology platforms. This comprehensive range includes THUNDER™ TR-FRET Cell Signalling Assay KitsTHUNDER™ TR-FRET Biomarker Assay Kits and THUNDER™ TR-FRET cAMP Assay Kit, all of which are invaluable for advancing research in this field and are available from 2BScientific.

Poly-Dtech

Poly Dtech LogoPoly-Dtech presents a comprehensive range of lanthanide-based fluorophore-conjugated streptavidin products, including their Bright-Dtech series. These specialised reagents are optimised for TR-FRET assays, enabling researchers to capture and detect biotinylated molecules for diverse applications, such as protein-protein interaction studies, biomolecular assays, and drug discovery research. These products offer advantages like fast and wash-free protocols, minimal background noise, low sample consumption, and significantly improved limit of detection (LOD).