Alpha Synuclein Antibody, Clone 3F8: Biotin Product Size(s) 100 ug £504.00 SMC-532D-BI Add to order Added to order Academic Pricing Please contact us for academic pricing. Contact Us About this Product SKU: SMC-532D-BI Additional Names: Alpha Synuclein Antibody, Non-A beta component of AD amyloid Antibody, Non-A4 component of amyloid precursor Antibody, NACP Antibody, SNCA Antibody, PARK1 Antibody, PARK 1 Antibody, alphaSYN Antibody, PARK 4 antibody, PARK4 antibody, Parkinson disease familial 1 antibody, Parkinson disease (autosomal dominant, Lewy body) 4 antibody, SYN antibody Application: Dot Blot, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot CE/IVD: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only. Clone: 3F8 Clonality: Monoclonal Conjugate: Biotin Concentration: 1 mg/ml Extra Details: Alpha-Synuclein (SNCA) is expressed predominantly in the brain, where it is concentrated in presynaptic nerve terminals (1). Alpha-synuclein is highly expressed in the mitochondria of the olfactory bulb, hippocampus, striatum and thalamus (2). Functionally, it has been shown to significantly interact with tubulin (3), and may serve as a potential microtubule-associated protein. It has also been found to be essential for normal development of the cognitive functions; inactivation may lead to impaired spatial learning and working memory (4). SNCA fibrillar aggregates represent the major non A-beta component of Alzheimers disease amyloid plaque, and a major component of Lewy body inclusions, and Parkinson's disease. Parkinson's disease (PD) is a common neurodegenerative disorder characterized by the progressive accumulation in selected neurons of protein inclusions containing alpha-synuclein and ubiquitin (5, 6). Gene Details: Snca Host: Mouse Immunogen: Mouse alpha synuclein aggregate Isotype: IgG1 Protein Details: O55042 Purification: Protein G Purified Reactivities: Human, Mouse, Rat Shipping Conditions: Blue Ice Storage Conditions: 2-8[o]C Supplier: StressMarq Biosciences Type: Antibody: Monoclonal Antibody Size: 100 ug Preservative: 0.09% Sodium azide Accession: NP_001035916.1 Need Help?