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Antibodies

TASK1 Potassium Channel Antibody, Clone N374/48: PerCP

Product Sizes
100 ug
SMC-473D-PCP-100UG
About this Product
SKU:
SMC-473D-PCP
Additional Names:
Potassium channel subfamily K member 3 Antibody, KCNK3 Antibody, Acid sensitive potassium channel protein TASK 1 Antibody, Cardiac two pore background K(+) channel Antibody, cTBAK 1 Antibody, K2p3.1 Antibody, KCNK9 Antibody, OAT1 Antibody, potassium channel subfamily K member 3 Antibody, rTASK Antibody, TASK 1 Antibody, TBAK1 Antibody, TWIK related acid sensitive K+ channel Antibody, Two pore potassium channel KT3.1 Antibody, Two pore K(+) channel KT3.1 Antibody
Application:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
Buffer:
PBS
CE/IVD:
RUO
translate.label.attr.clone:
N374/48 (Formerly sold as S374-48)
Clonality:
Monoclonal
Conjugate:
PerCP
Concentration:
1 mg/ml
Extra Details:
K+ channels are divided into three subclasses reflecting the number of transmembrane segments (TMS), which are designated 6TMS, 4TMS and 2TMS. Members of the 4TMS class contain two distinct pore regions and include TWIK, TREK, TRAAK and TASK. TASK channels are highly sensitive to external pH in the physiological range. TASK-1 is expressed in brain and in rat heart, with high levels of expression in the right atrium. TASK-2, mainly expressed in kidney, is localized in cortical distal tubules and collecting ducts, suggesting a role in renal K+ transport. TASK-3 from rat cerebellum shares 54% identity with TASK-1, but less than 30% identity with TASK-2 and other tandem pore K+ channels.
Host:
Mouse
Immunogen:
Fusion protein amino acids 251-411 (cytoplasmic C-terminus) of rat Acid-sensitive potassium channel protein TASK or TASK1. Mouse: 96% identity (156/161 amino acids identical). Human: 76% identity (163/161 amino acids identical). <30% identity with TASK3.
Isotype:
IgG2b
Purification:
Protein G Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Specificity:
Detects ~50kDa. Does not cross-react with TASK3.
Storage Conditions:
See Manual
Supplier:
StressMarq Biosciences
Type:
Antibody: Monoclonal Antibody