IL-34 Antibody
Product Sizes
100 ug
600-401-C06-100UG
About this Product
- SKU:
- 600-401-C06
- Additional Names:
- IL-34, Interleukin-34|IL34
- Application:
- ELISA, Western Blot
- Buffer:
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride
- CE/IVD:
- RUO
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- Interleukin-34 (IL-34) was identified through a functional screening of a library of secreted proteins after transfection of an embryonic kidney cell line with recombinant cDNAs. Flow cytometry and monocyte viability assays demonstrated increased survival and/or proliferation of monocytes induced by IL-34 and specific binding of IL-34 to CD14+ monocytes. IL-34 is a second ligand to the colony stimulating factor (CSF)-1 receptor in addition to CSF1. Like CSF1, IL-34 stimulates phosphorylation of ERK1 and ERK2 in human monocytes and induces differentiation of bone marrow cells into macrophages. Anti-IL-34 Antibody is ideal for investigators involved in Cell Signaling, Immunology and Signal Transduction research.
- Formulation:
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
- Host:
- Rabbit
- Immunogen:
- Anti-IL-34 Antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to a region near the amino terminus of human IL-34 protein.
- Isotype:
- IgG
- Physical State:
- Liquid
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Dry Ice
- Specificity:
- Anti-IL 34 is affinity chromatography purified via peptide column. The IL34 gene is conserved in chimpanzee, dog, cow, mouse, and rat. This antibody reacts with IL-34 from human, mouse, and rat sources. Reactivity with IL-34 from other sources has not been determined.
- Storage Conditions:
- 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Rockland Inc
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:https://www.rockland.com/search/?searchString=600-401-C06
