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Antibodies

Avian Influenza Hemagglutinin 4 Antibody

Product Sizes
100 ug
600-101-G79-100UG
About this Product
SKU:
600-101-G79
Additional Names:
Avian Influenza Hemagglutinin 4, AFHA-4, Avian flu hemagglutinin, Avian influenza H5|HA
Application:
ELISA
Buffer:
0.02 M Potassium Phosphate, 0.15 M Sodium Chloride
CE/IVD:
RUO
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
Anti-Avian Influenza Hemmagglutinin 4 antibody detects the internal portion of Hemagglutinin protein. Influenza A virus is a major public health threat, killing more than 30, 000 people per year in the USA. Novel influenza virus strains caused by genetic drift and viral recombination emerge periodically to which humans have little or no immunity, resulting in devastating pandemics. Influenza A can exist in a variety of animals; however it is in birds that all subtypes can be found. These subtypes are classified based on the combination of the virus coat glycoproteins hemagglutinin (HA) and neuraminidase (NA) subtypes. During 1997, an H5N1 avian influenza virus was determined to be the cause of death in 6 of 18 infected patients in Hong Kong. There was some evidence of human to human spread of this virus, but it is thought that the transmission efficiency was fairly low. HA interacts with cell surface proteins containing oligosaccharides with terminal sialyl residues. Virus isolated from a human infected with the H5N1 strain in 1997 could bind to oligosaccharides from human as well as avian sources, indicating its species-jumping ability. Anti-Avian Influenza Hemmagglutinin 4 antibodies are ideal for investigators involved in infectious disease research.
Formulation:
0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Host:
Goat
Immunogen:
Avian Influenza Hemmagglutinin 4 Antibody was produced from whole goat serum prepared by repeated immunizations with a synthetic peptide corresponding to an internal region of the Hemagglutinin protein. Efforts were made to use relatively conserved regions of the viral sequence as the antigen.
Isotype:
IgG
Physical State:
Liquid
Reactivities:
Virus
Shipping Conditions:
Dry Ice
Specificity:
Anti-Avian Influenza Hemmagglutinin 4 Antibody was affinity purified from monospecific antiserum by immunoaffinity purification. A BLAST analysis was used to suggest cross-reactivity with Avian Influenza Hemmagglutinin 4 with virus based on 100% homology with the immunizing sequence. Cross-reactivity with Avian Influenza Hemmagglutinin 4 from other sources has not been determined.
Storage Conditions:
-20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles.
Supplier:
Rockland Inc
Type:
Antibody: Polyclonal Antibody