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Antibodies

AntiSSeL Antibody

Product Sizes
AntiSSeL Antibody
£543.00
AB-0601-0250
Academic Pricing
Please contact us for academic pricing.
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About this Product
SKU:
AB-0601-0250
Application:
Western Blot
Extra Details:
A novel virulence factor was identified in Salmonella enterica serovar Typhimurium. This factor was determined to be a protein named SseL. SseL is translocated from the bacteria into the infected cell by a type III secretion system. SseL has deubiquitylating activity in vitro and infection of cells with a SseL mutant leads to the accumulation of ubiquitylated proteins. This mutant strain also fails to cause macrophage cell death, which has been implicated in the spread and systemic infection of Salmonella. Other serovars, including Typhi, Paratyphi A and Choleraesuis contain sequences encoding a protein nearly identical to SseL suggesting that deubiquitylating enzymes play an important role in the pathogenesis of other Salmonella serovars.
Host:
Chicken/Avian
Reactivities:
Bacteria
Shipping Conditions:
Dry Ice
Storage Conditions:
-20[o]C
Size:
250 ug
Supplier:
LifeSensors
Type:
Antibody