Angiotensin II
Product Sizes
Angiotensin II
£118.00
AT-010
About this Product
- SKU:
- AT-010
- Additional Names:
- Ang II
- CAS Number:
- 4474-91-3
- Extra Details:
- Angiotensin II (Ang II) is an endogenous active peptide of the renin-angiotensin system. Angiotensin II is produced from angiotensin I through the removal of two C-terminal residues by angiotensin converting enzyme (ACE), primarily within the lung. Angiotensin II binds to AT1 and AT2 receptors and plays a central role in the regulation of blood pressure and electrolyte homeostasis. Angiotensin II also mediates vasoconstriction, thirst, release of vasopressin and aldosterone, renal sodium reabsorption, fibrosis, inflammation, angiogenesis, vascular aging, and atherosclerosis.
- Molecular Weight:
- 1046.2
- Purity:
- >95% by hplc
- References:
- <p>Fyhrquist et al (1995) Role of angiotensin II in blood pressure regulation and in the pathophysiology of cardiovascular disorders. J Hum Hypertens. Suppl 5 S19-24. <a href="https://pubmed.ncbi.nlm.nih.gov/8583476/" target="_blank" rel="nofollow">PMID: 8583476</a></p><p>Potts et al (1999) Activation of brain neurons by circulating angiotensin II: direct effects and baroreceptor-mediated secondary effects. Neuroscience 90(2) 581 <a href="https://pubmed.ncbi.nlm.nih.gov/10215161/" target="_blank" rel="nofollow">PMID: 10215161</a></p><p>Cheng et al (2005) Angiotensin II and Vascular Inflammation. Med Sci Monit. <strong>11</strong>(6) RA194 <a href="PMID: 15917731" target="_blank" rel="nofollow">PMID: 15917731</a></p>
- Sequence:
- H-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-OH
- Shipping Conditions:
- Ambient
- Storage Conditions:
- Store dry, frozen and in the dark
- Size:
- 5 mg
- Supplier:
- Isca Biochemicals
- Solubility:
- Soluble to 1 mg/ml in water
- Formula:
- C50H71N13O12