Anti Collagen Alpha-1(XII) Chain monoclonal antibody (Clone 378D5)
Product Sizes
2 ml
CAC-PRPG-CO12-M01-2ML
About this Product
- SKU:
- CAC-PRPG-CO12-M01
- Application:
- ELISA, IHC-Frozen, IHC-Paraffin, Immunoprecipitation, Western Blot
- translate.label.attr.clone:
- Clone 378d5
- Clonality:
- Monoclonal
- Extra Details:
- Type XII collagen is a member of the FACIT (fibril-associated collagens with interrupted triple helices) collagen subfamily currently composed of 9 members (collagen types VII, IX, XII, XIV, XVI, XIX, XX, and XXI). Type XII collagen is a homotrimer composed of three alpha-1(XII) chains with an approximate Mr of 220 kDa. This collagen was originally found in prevalent association with type I collagen in tendons, ligaments, perichondrium, and periosteum and all dense connective tissues, but more recent studies also document association of the collagen with basement membranes. The type XII-type I collagen connection is thought to modify the interactions between collagen type I fibrils and the surrounding matrix such as to create specific macromolecular configuration of the ECM. Alternatively spliced transcript variants encoding different isoforms of the collagen have been identified. Rotary shadowing/TEM analyses shows a structure with a thin 75-nm tail, which is frequently kinked, attached through a central globule to three finger-like projections, each 60 nm long., CAC
- Host:
- Mouse
- Immunogen:
- Collagen Alpha-1(XII) Chain
- Reactivities:
- Avian, Bovine, Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C
- Supplier:
- Cosmo Bio Ltd
- Type:
- Antibody: Monoclonal Antibody